Structure of PDB 8vtu Chain 12

Receptor sequence
>8vtu12 (length=70) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MKLSEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKI
RDLKRQIARLLTVLNEKRRQ
3D structure
PDB8vtu Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain12
Resolution2.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 12 M1 K2 L3 R7 L10 R14 K29 S45 Q46 N47 H48 I50 R51 R55 A58 R59 L61 T62 N65 M1 K2 L3 R7 L10 R14 K29 S45 Q46 N47 H48 I50 R51 R55 A58 R59 L61 T62 N65
BS02 MG 12 K54 I57 K54 I57
External links
PDB RCSB:8vtu, PDBe:8vtu, PDBj:8vtu
PDBsum8vtu
PubMed39039256
UniProtQ5SHP6|RL29_THET8 Large ribosomal subunit protein uL29 (Gene Name=rpmC)

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