Structure of PDB 7qb5 Chain 111

Receptor sequence
>7qb5111 (length=281) Species: 12089 (Coxsackievirus A24) [Search protein sequence]
PTAQSTPLTSGVNSQEVPALTAVETGASGQAVPSDVIETRHVVNYKTRSE
STLESFFGRSACVTILEVENFNATTDADRKKQFTTWAITYTDTVQLRRKL
EFFTYSRFDLEMTFVITERYYASNTGHARNQVYQLMYIPPGAPRPTAWDD
YTWQSSSNPSVFYTYGSAPPRMSIPYVGIANAYSHFYDGFARVPLKDETV
DSGDTYYGLVTINDFGTLAVRVVNEYNPARITSKIRVYMKPKHVRCWCPR
PPRAVPYRGEGVDFKQDSITPLTAVENINTF
3D structure
PDB7qb5 Exploring divalent conjugates of 5- N -acetyl-neuraminic acid as inhibitors of coxsackievirus A24 variant (CVA24v) transduction.
Chain111
Resolution1.728 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA 111 Y725 A726 S727 Y121 A122 S123
BS02 CA 111 T606 A607 S609 N648 T2 A3 S5 N44
BS03 CA 111 T613 S614 S638 I641 T9 S10 S34 I37
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:7qb5, PDBe:7qb5, PDBj:7qb5
PDBsum7qb5
PubMed35425270
UniProtV9VEF3

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