Structure of PDB 6tsd Chain 111

Receptor sequence
>6tsd111 (length=281) Species: 12089 (Coxsackievirus A24) [Search protein sequence]
PTAQSTPLTSGVNSQEVPALTAVETGASGQAVPSDVIETRHVVNYKTRSE
STLESFFGRSACVTILEVENFNATTDADRKKQFTTWAITYTDTVQLRRKL
EFFTYSRFDLEMTFVITERYYASNTGHARNQVYQLMYIPPGAPRPTAWDD
YTWQSSSNPSVFYTYGSAPPRMSIPYVGIANAYSHFYDGFARVPLKDETV
DSGDTYYGLVTINDFGTLAVRVVNEYNPARITSKIRVYMKPKHVRCWCPR
PPRAVPYRGEGVDFKQDSITPLTAVENINTF
3D structure
PDB6tsd Pentavalent Sialic Acid Conjugates Block Coxsackievirus A24 Variant and Human Adenovirus Type 37-Viruses That Cause Highly Contagious Eye Infections.
Chain111
Resolution1.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA 111 Y145 A146 S147 Y121 A122 S123
BS02 CA 111 T33 S34 S58 I61 T9 S10 S34 I37
BS03 CA 111 N94 W172 V246 N248 N70 W148 V222 N224
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:6tsd, PDBe:6tsd, PDBj:6tsd
PDBsum6tsd
PubMed32845119
UniProtV9VEF3

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