Structure of PDB 8pj3 Chain 1

Receptor sequence

>8pj31 (length=588) Species: 9606 (Homo sapiens) [Search protein sequence]

GDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITN
DFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDF
DKYMTISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGDRTSIF
WNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGEKFKQIQ
RFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFH
CESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKD
FSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHW
QKNGDYLCVKVDRVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSK
FAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANTIFWSPQGQFVVLA
GLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHK
VDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKK
YSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMA

3D structure

PDB

8pj3 UCSF ChimeraX: Structure visualization for researchers, educators, and developers

Chain

Resolution

3.7 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	1	D488 K726	D319 K550

External links

PDB	RCSB:8pj3, PDBe:8pj3, PDBj:8pj3
PDBsum	8pj3
PubMed
UniProt	P55884\|EIF3B_HUMAN Eukaryotic translation initiation factor 3 subunit B (Gene Name=EIF3B)

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