Structure of PDB 8pj1 Chain 1

Receptor sequence

>8pj11 (length=588) Species: 9606 (Homo sapiens) [Search protein sequence]

GDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITN
DFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDF
DKYMTISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGDRTSIF
WNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGEKFKQIQ
RFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFH
CESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKD
FSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHW
QKNGDYLCVKVDRVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSK
FAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANTIFWSPQGQFVVLA
GLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHK
VDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKK
YSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMA

3D structure

PDB

8pj1 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining

Chain

Resolution

3.4 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	1	D488 D723	D319 D547

External links

PDB	RCSB:8pj1, PDBe:8pj1, PDBj:8pj1
PDBsum	8pj1
PubMed
UniProt	P55884\|EIF3B_HUMAN Eukaryotic translation initiation factor 3 subunit B (Gene Name=EIF3B)

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