Structure of PDB 8esz Chain 1

Receptor sequence
>8esz1 (length=315) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
MFYMEFILSLIGSLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLM
GIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFV
KLYSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYE
VSLALILLSFIFLIGSYNMIYFFFYQVYMWFLIILFPMALVWVSISLAET
NRTPFDFAEGESELVSGFNVEYSSGGFALIFMAEYASILFMSMLFCVIFL
GCDVFNLLFYMKLTFISFVFIWVRGTLPRFRYDKLMYLAWKCFLSFSLNY
LLFFIGFKILLFSLL
3D structure
PDB8esz Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state.
Chain1
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 U10 1 A25 R32 L35 D58 F231 M232 A25 R32 L35 D58 F231 M232
BS02 WSF 1 F87 S104 F105 F87 S104 F105
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8esz, PDBe:8esz, PDBj:8esz
PDBsum8esz
PubMed36952377
UniProtC7DZL9

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