Structure of PDB 7jg9 Chain 1

Receptor sequence
>7jg91 (length=81) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence]
PNAIITAGALIGGGLIMGGGAIGAGIGDGIAGNALISGIARQPEAQGRLF
TPFFITVGLVEAAYFINLAFMALFVFATPGL
3D structure
PDB7jg9 Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline.
Chain1
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BQ1 1 A66 A67 A62 A63
Gene Ontology
Molecular Function
GO:0008289 lipid binding
GO:0015078 proton transmembrane transporter activity
GO:0016787 hydrolase activity
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain
GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)

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Cellular Component
External links
PDB RCSB:7jg9, PDBe:7jg9, PDBj:7jg9
PDBsum7jg9
PubMed33299175
UniProtA0R205

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