Structure of PDB 6esb Chain 1

Receptor sequence
>6esb1 (length=347) Species: 1891762 (Betapolyomavirus hominis) [Search protein sequence]
PKKPKEPVQVPKLLIKGGVEVLEVKTGVDAITEVECFLNPEMGDPDENLR
GFSLKLSAENDFSSDSPERKMLPCYSTARIPLPNLNEDLTCGNLLMWEAV
TVQTEVIGITSMLNLHAGSQKVHEHGGGKPIQGSNFHFFAVGGDPLEMQG
VLMNYRTKYPDGTITPKNPTAQSQVMNTDHKAYLDKNNAYPVECWVPDPS
RNENTRYFGTFTGGENVPPVLHVTNTATTVLLDEQGVGPLCKADSLYVSA
ADICGLFTNSSGTQQWRGLARYFKIRLRKRSVKNPYPISFLLSDLINRRT
QRVDGQPMYGMESQVEEVRVFDGTERLPGDPDMIRYIDKQGQLQTKM
3D structure
PDB6esb The Structure of an Infectious Human Polyomavirus and Its Interactions with Cellular Receptors.
Chain1
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA 1 L67 N272 S274 T276 Q278 L54 N259 S261 T263 Q265
BS02 CA 1 S213 E216 S200 E203
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0019062 virion attachment to host cell
GO:0046718 symbiont entry into host cell
GO:0075513 caveolin-mediated endocytosis of virus by host cell
Cellular Component
GO:0019028 viral capsid
GO:0039620 T=7 icosahedral viral capsid
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6esb, PDBe:6esb, PDBj:6esb
PDBsum6esb
PubMed29706532
UniProtP03088|VP1_POVBK Major capsid protein VP1

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