Structure of PDB 4r67 Chain 1

Receptor sequence
>4r671 (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]
RFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKT
VIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRR
FFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLD
NQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTK
EGIREETVSLRKD
3D structure
PDB4r67 Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib.
Chain1
Resolution2.89 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.25.1: proteasome endopeptidase complex.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3BV 1 R100 P126 R100 P126
Gene Ontology
Biological Process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0005839 proteasome core complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4r67, PDBe:4r67, PDBj:4r67
PDBsum4r67
PubMed25599644
UniProtP20618|PSB1_HUMAN Proteasome subunit beta type-1 (Gene Name=PSMB1)

[Back to BioLiP]