Structure of PDB 3cxc Chain 1

Receptor sequence
>3cxc1 (length=46) Species: 2238 (Haloarcula marismortui) [Search protein sequence]
GKKSKATKKRLAKLDNQNSRVPAWVMLKTDERNHKRRHWRRNDTDE
3D structure
PDB3cxc Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
Chain1
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 1 G1 K2 K3 K5 A6 K8 R10 L11 K13 N16 Q17 S19 P22 W24 V25 L27 K28 T29 D30 R35 H37 R40 H41 W42 R43 N45 T47 G1 K2 K3 K5 A6 K8 R10 L11 K13 N16 Q17 S19 P22 W24 V25 L27 K28 T29 D30 R32 H34 R37 H38 W39 R40 N42 T44 PDBbind-CN: IC50=4.6uM
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:3cxc, PDBe:3cxc, PDBj:3cxc
PDBsum3cxc
PubMed18947996
UniProtP22452|RL39_HALMA Large ribosomal subunit protein eL39 (Gene Name=rpl39e)

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