Structure of PDB 2rs1 Chain 1

Receptor sequence
>2rs11 (length=273) Species: 169066 (Human rhinovirus sp.) [Search protein sequence]
TVASISSGPKHTQKVPILTANETGATMPVLPSDSIETRTTYMHFNGSETD
VECFLGRAACVHVTEIQNKDATGIDNHREAKLFNDWKINLSSLVQLRKKL
ELFTYVRFDSEYTILATASQPDSANYSSNLVVQAMYVPPGAPNPKEWDDY
TWQSASNPSVFFKVGDTSRFSVPYVGLASAYNCFYDGYSHDDAETQYGIT
VLNHMGSMAFRIVNEHDEHKTLVKIRVYHRAKHVEAWIPRAPRALPYTSI
GRTNYPKNTEPVIKKRKGDIKSY
3D structure
PDB2rs1 Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Chain1
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 W84 1 I104 L106 Y128 Y152 S175 V176 F186 V188 Y197 N219 M221 I88 L90 Y112 Y136 S159 V160 F170 V172 Y181 N203 M205
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:2rs1, PDBe:2rs1, PDBj:2rs1
PDBsum2rs1
PubMed2558377
UniProtP03303|POLG_HRV14 Genome polyprotein

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