Structure of PDB 2fug Chain 1

Receptor sequence
>2fug1 (length=432) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
SGLDPRFERTLYAHVGKEGSWTLDYYLRHGGYETAKRVLKEKTPDEVIEE
VKRSGLRGRGGAGFPTGLKWSFMPKDDGKQHYLICNADESEPGSFKDRYI
LEDVPHLLIEGMILAGYAIRATVGYIYVRGEYRRAADRLEQAIKEARARG
YLGKNLFGTDFSFDLHVHRGAGAYICGEETALMNSLEGLRANPRLKPPFP
AQSGLWGKPTTINNVETLASVVPIMERGADWFAQMGTEQSKGMKLYQISG
PVKRPGVYELPMGTTFRELIYEWAGGPLEPIQAIIPGGSSTPPLPFTEEV
LDTPMSYEHLQAKGSMLGTGGVILIPERVSMVDAMWNLTRFYAHESCGKC
TPCREGVAGFMVNLFAKIGTGQGEEKDVENLEALLPLIEGRSFCPLADAA
VWPVKGSLRHFKDQYLALAREKRPVPRPSLWR
3D structure
PDB2fug Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
Chain1
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 1 P199 S352 C353 G354 C356 C359 F399 C400 L402 A403 P193 S346 C347 G348 C350 C353 F393 C394 L396 A397
BS02 FMN 1 G64 K75 N92 D94 E95 S96 Y180 G183 E184 N219 N220 P401 G58 K69 N86 D88 E89 S90 Y174 G177 E178 N213 N214 P395
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0010181 FMN binding
GO:0046872 metal ion binding
GO:0048038 quinone binding
GO:0051287 NAD binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0045271 respiratory chain complex I

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2fug, PDBe:2fug, PDBj:2fug
PDBsum2fug
PubMed16469879
UniProtQ56222|NQO1_THET8 NADH-quinone oxidoreductase subunit 1 (Gene Name=nqo1)

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