Structure of PDB 1rug Chain 1

Receptor sequence
>1rug1 (length=273) Species: 12131 (rhinovirus B14) [Search protein sequence]
TVASISSGPKHTQKVPILTANETGATMPVLPSDSIETRTTYMHFNGSETD
VECFLGRAACVHVTEIQNKDATGIDNHREAKLFNDWKINLSSLVQLRKKL
ELFTYVRFDSEYTILATASQPDSANYSSNLVVQAMYVPPGAPNPKEWDDY
TWQSASNPSVFFKVGDTSRFSVPYVGLASAYNCFYDGYSHDDAETQYGIT
VLSHMGSMAFRIVNEHDEHKTLVKIRVYHRAKHVEAWIPRAPRALPYTSI
GRTNYPKNTEPVIKKRKGDIKSY
3D structure
PDB1rug Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
Chain1
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 W35 1 L106 Y128 Y152 P174 F186 V188 V191 Y197 M221 L90 Y112 Y136 P158 F170 V172 V175 Y181 M205
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1rug, PDBe:1rug, PDBj:1rug
PDBsum1rug
PubMed7473717
UniProtP03303|POLG_HRV14 Genome polyprotein

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