Structure of PDB 1r09 Chain 1

Receptor sequence
>1r091 (length=273) Species: 12131 (rhinovirus B14) [Search protein sequence]
TVASISSGPKHTQKVPILTANETGATMPVLPSDSIETRTTYMHFNGSETD
VECFLGRAACVHVTEIQNKDATGIDNHREAKLFNDWKINLSSLVQLRKKL
ELFTYVRFDSEYTILATASQPDSANYSSNLVVQAMYVPPGAPNPKEWDDY
TWQSASNPSVFFKVGDTSRFSVPYVGLASAYNCFYDGYSHDDAETQYGIT
VLNHMGSMAFRIVNEHDEHKTLVKIRVYHRAKHVEAWIPRAPRALPYTSI
GRTNYPKNTEPVIKKRKGDIKSY
3D structure
PDB1r09 Human rhinovirus 14 complexed with antiviral compound R 61837.
Chain1
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 JEN 1 I104 F124 S126 Y128 Y152 V188 Y197 I88 F108 S110 Y112 Y136 V172 Y181
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1r09, PDBe:1r09, PDBj:1r09
PDBsum1r09
PubMed1847215
UniProtP03303|POLG_HRV14 Genome polyprotein

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