Structure of PDB 1r08 Chain 1

Receptor sequence
>1r081 (length=273) Species: 12131 (rhinovirus B14) [Search protein sequence]
TVASISSGPKHTQKVPILTANETGATMPVLPSDSIETRTTYMHFNGSETD
VECFLGRAACVHVTEIQNKDATGIDNHREAKLFNDWKINLSSLVQLRKKL
ELFTYVRFDSEYTILATASQPDSANYSSNLVVQAMYVPPGAPNPKEWDDY
TWQSASNPSVFFKVGDTSRFSVPYVGLASAYNCFYDGYSHDDAETQYGIT
VLNHMGSMAFRIVNEHDEHKTLVKIRVYHRAKHVEAWIPRAPRALPYTSI
GRTNYPKNTEPVIKKRKGDIKSY
3D structure
PDB1r08 Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Chain1
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 W42 1 I104 L106 S107 L116 Y128 Y152 P174 V176 F186 V188 M221 M224 I88 L90 S91 L100 Y112 Y136 P158 V160 F170 V172 M205 M208
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1r08, PDBe:1r08, PDBj:1r08
PDBsum1r08
PubMed2558377
UniProtP03303|POLG_HRV14 Genome polyprotein

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