Structure of PDB 1po2 Chain 1

Receptor sequence
>1po21 (length=283) Species: 12081 (Human poliovirus 1 Mahoney) [Search protein sequence]
AATSRDALPNTEASGPTHSKEIPALTAVETGATNPLVPSDTVQTRHVVQH
RSRSESSIESFFARGACVTIMTVDNPASTTNKDKLFAVWKITYKDTVQLR
RKLEFFTYSRFDMELTFVVTANFTETNNGHALNQVYQIMYVPPGAPVPEK
WDDYTWQTSSNPSIFYTYGTAPARISVPYVGISNAYSHFYDGFSKVPLKD
QSAALGDSLYGAASLNDFGILAVRVVNDHNPTKVTSKIRVYLKPKHIRVW
CPRPPRAVAYYGPGVDYKDGTLTPLSTKDLTTY
3D structure
PDB1po2 Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Chain1
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 J77 1 I110 Y112 M132 L134 Y159 I194 V196 V199 Y205 F237 L240 I91 Y93 M113 L115 Y140 I175 V177 V180 Y186 F218 L221
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1po2, PDBe:1po2, PDBj:1po2
PDBsum1po2
PubMed15299887
UniProtP03300|POLG_POL1M Genome polyprotein

[Back to BioLiP]