Structure of PDB 1hrv Chain 1

Receptor sequence
>1hrv1 (length=273) Species: 12131 (rhinovirus B14) [Search protein sequence]
TVASISSGPKHTQKVPILTANETGATMPVLPSDSIETRTTYMHFNGSETD
VECFLGRAACVHVTEIQNKDATGIDNHREAKLFNDWKINLSSLVQLRKKL
ELFTYVRFDSEYTILATASQPDSANYSSNLVVQAMYVPPGAPNPKEWDDY
TWQSASNPSVFFKVGDTSRFSVPYVGLASAYNCFYDGYSHDDAETQYGIT
VLNHMGSMAFRIVNEHDEHKTLVKIRVYHRAKHVEAWIPRAPRALPYTSI
GRTNYPKNTEPVIKKRKGDIKSY
3D structure
PDB1hrv SDZ 35-682, a new picornavirus capsid-binding agent with potent antiviral activity.
Chain1
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SDZ 1 L106 S126 Y128 Y152 P174 F186 V188 Y197 M224 L90 S110 Y112 Y136 P158 F170 V172 Y181 M208
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1hrv, PDBe:1hrv, PDBj:1hrv
PDBsum1hrv
PubMed7741522
UniProtP03303|POLG_HRV14 Genome polyprotein

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