Structure of PDB 1c8m Chain 1

Receptor sequence
>1c8m1 (length=285) Species: 31708 (rhinovirus A16) [Search protein sequence]
NPVERYVDEVLNEVLVVPNINQSHPTTSNAAPVLDAAETGHTNKIQPEDT
IETRYVQSSQTLDEMSVESFLGRSGCIHESVLDIVDNYNDQSFTKWNINL
QEMAQIRRKFEMFTYARFDSEITMVPSVAAKDGHIGHIVMQYMYVPPGAP
IPTTRDDYAWQSGTNASVFWQHGQPFPRFSLPFLSIASAYYMFYDGYDGD
TYKSRYGTVVTNDMGTLCSRIVTSEQLHKVKVVTRIYHKAKHTKAWCPRP
PRAVQYSHTHTTNYKLSSEVHNDVAIRPRTNLTTV
3D structure
PDB1c8m Structure of a Human Common Cold Virus and Functional Relationship to Other Picornaviruses
Chain1
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide 1 V3 Y6 E9 D63 S66 E68 S180 K241 H242 V3 Y6 E9 D63 S66 E68 S180 K241 H242
BS02 W11 1 I98 L100 M124 Y142 M143 Y144 F179 L181 Y190 M214 L217 I98 L100 M124 Y142 M143 Y144 F179 L181 Y190 M214 L217
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1c8m, PDBe:1c8m, PDBj:1c8m
PDBsum1c8m
PubMed
UniProtQ82122|POLG_HRV16 Genome polyprotein

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