Structure of PDB 8cvm Chain 0
Receptor sequence
>8cvm0 (length=50) Species:
1747
(Cutibacterium acnes) [
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DVRPKITLACTECKERNYITKKNRRNNPDRMEMAKFCPRCRKHTAHRETR
3D structure
PDB
8cvm
Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Chain
0
Resolution
2.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
rna
0
R9 E21 R22 Y24 I25 T26 K27 N29 N32 M37 M39 K41 F42 R45 K48 H49
R3 E15 R16 Y18 I19 T20 K21 N23 N26 M31 M33 K35 F36 R39 K42 H43
BS02
ZN
0
C16 C19 C43
C10 C13 C37
Gene Ontology
Molecular Function
GO:0003735
structural constituent of ribosome
Biological Process
GO:0006412
translation
Cellular Component
GO:0005737
cytoplasm
GO:0005840
ribosome
GO:1990904
ribonucleoprotein complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:8cvm
,
PDBe:8cvm
,
PDBj:8cvm
PDBsum
8cvm
PubMed
36864821
UniProt
Q6A6J5
|RL331_CUTAK Large ribosomal subunit protein bL33A (Gene Name=rpmG1)
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