Structure of PDB 8cre Chain 0

Receptor sequence

>8cre0 (length=170) Species: 5476 (Candida albicans) [Search protein sequence]

RLNEYQVIGRNLPTESVPEPKLFRMRIFAPNTVVAKSRYWYFLQKLHKVK
KASGEIVSVNIISEAKPTKVKTFGIWLRYESRSGIHNMYKEYRDVTRVGA
VETMYQDLAARHRARFRSIHILKVVELEKTDDVKRQYVKQFLTKDLKFPL
PHRVQKSKKLFQATAPTTFY

3D structure

PDB

8cre Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	0	N62 S65 E66 K68 P69 S83 R84 S85 H88 M90 Y91 K92 Q108 A111 A112 R113 H114 R115 R117 T132 R137 Y139 L144 T145 K146 P153 H154 R155 Q157 S159 K161 Q164 A165 A167 P168 T169 T170 F171	N60 S63 E64 K66 P67 S81 R82 S83 H86 M88 Y89 K90 Q106 A109 A110 R111 H112 R113 R115 T130 R135 Y137 L142 T143 K144 P151 H152 R153 Q155 S157 K159 Q162 A163 A165 P166 T167 T168 F169
BS02	rna	0	K23 S39 Y43 Q46 H49 K50 V51 K52 K53 R84 R119	K21 S37 Y41 Q44 H47 K48 V49 K50 K51 R82 R117

External links

PDB	RCSB:8cre, PDBe:8cre, PDBj:8cre
PDBsum	8cre
PubMed
UniProt	A0A8H6BZJ3

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