Structure of PDB 7q38 Chain A Binding Site BS21

Receptor Information
>7q38 Chain A (length=228) Species: 64091 (Halobacterium salinarum NRC-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ITGRPEWIWLALGAALMGLGALYFLVKGMGVSDPDAKKFYAITALVPAIA
FTMYLSMLLGYGLTMVPFGGEQNPIYWARYADWLFTTPLLLLDLALLVDA
DQGTILALVGADGIMIGTGLVGALTKVYSYRFVWWAISTAAMLYILYVLF
FGFTSKAESMRPEVASTFKVLRNVTVVLWSAYPVVWLIGSEGAGIVPLNI
ETLLFMVLDVSAKVGFGLILLRSRAIFG
Ligand information
Ligand IDAR
InChIInChI=1S/Ar
InChIKeyXKRFYHLGVUSROY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Ar]
FormulaAr
NameARGON
ChEMBL
DrugBank
ZINC
PDB chain7q38 Chain A Residue 357 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7q38 High-pressure crystallography shows noble gas intervention into protein-lipid interaction and suggests a model for anaesthetic action.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		A44 I45
Binding residue
(residue number reindexed from 1)		A41 I42
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0009881 photoreceptor activity
GO:0015454 light-driven active monoatomic ion transmembrane transporter activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0007602 phototransduction
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7q38, PDBe:7q38, PDBj:7q38
PDBsum7q38
PubMed35422073
UniProtP02945|BACR_HALSA Bacteriorhodopsin (Gene Name=bop)

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