Structure of PDB 5oxk Chain A Binding Site BS15

Receptor Information
>5oxk Chain A (length=437) Species: 264199 (Streptococcus thermophilus LMG 18311) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRAT
AASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALP
FGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGI
NLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHY
LRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTI
VAIAIPVFYFAWMIVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSS
WFPVSWFQSLNPLFIMLYTPFFAWLWTAWPSSPTKFAVGLMFAGLSFLLM
AIPGALYGTSGKVSPLWLVGSWALVILGEMLISPNSQMMSMWFLSSSVGS
ALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLS
Ligand information
Ligand IDGLN
InChIInChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
InChIKeyZDXPYRJPNDTMRX-VKHMYHEASA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CC(=O)N)C(C(=O)O)N
OpenEye OEToolkits 1.5.0C(CC(=O)N)[C@@H](C(=O)O)N
ACDLabs 10.04O=C(N)CCC(N)C(=O)O
CACTVS 3.341N[CH](CCC(N)=O)C(O)=O
CACTVS 3.341N[C@@H](CCC(N)=O)C(O)=O
FormulaC5 H10 N2 O3
NameGLUTAMINE
ChEMBLCHEMBL930
DrugBankDB00130
ZINCZINC000001532526
PDB chain5oxk Chain A Residue 519 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5oxk Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter.
Resolution2.38 Å
Binding residue
(original residue number in PDB)		R26 Y30 Y68 K126 I155 W296 W427 S431
Binding residue
(residue number reindexed from 1)		R21 Y25 Y63 K121 I150 W279 W392 S396
Annotation score4
Binding affinityPDBbind-CN: -logKd/Ki=2.17,Kd=6.82mM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0022857 transmembrane transporter activity
GO:0042802 identical protein binding
GO:1904680 peptide transmembrane transporter activity
Biological Process
GO:0006857 oligopeptide transport
GO:0015833 peptide transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5oxk, PDBe:5oxk, PDBj:5oxk
PDBsum5oxk
PubMed29429879
UniProtQ5M4H8

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