Structure of PDB 5t9t Chain B Binding Site BS14

Receptor Information
>5t9t Chain B (length=526) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPES
GDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAP
LFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVT
EKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQ
VTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAF
HNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHC
SIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGD
VYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPP
LSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDL
GSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLT
LQARDHGSPTLSANVSMRVLVGDRND
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5t9t Chain B Residue 614 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5t9t gamma-Protocadherin structural diversity and functional implications.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		D491 E493 D527
Binding residue
(residue number reindexed from 1)		D490 E492 D526
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5t9t, PDBe:5t9t, PDBj:5t9t
PDBsum5t9t
PubMed27782885
UniProtQ8K486

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