Structure of PDB 5szn Chain A Binding Site BS13

Receptor Information
>5szn Chain A (length=523) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IRYSVPEETEKGYIVGNISKDLGLEPERGVRIISKGKTQLFSLSPRSGSL
VTAGRIDREELCAQSATCLLNFKVLVEDRVKLYGVEVEVVDINDNAPKFE
AENLFVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQT
GDDGTINPELVLERTLDREEEPTHHLVLTAYDGGNPRRSSTALIQVTVLD
TNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKI
NEKHSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDGGGLKGRTKVV
VMVEDVNDNRPEVTITSLFSPVREDAPPGTVILLFNAHDQDSGKNGQVVC
SIQENPSFKLENSVDDYYRLLTAQILDREKASEYNITVTATDRGTPSMST
EVHITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDDEEN
AKVTYSLVENTIQGAPLSSYVSINSDTGVLYALQSFDYEQFQNLQMQVKA
SDNGHPPLSSNVSLSVFLLDQND
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5szn Chain A Residue 615 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5szn gamma-Protocadherin structural diversity and functional implications.
Resolution2.944 Å
Binding residue
(original residue number in PDB)		N99 N101 D131 D133 N137 D188
Binding residue
(residue number reindexed from 1)		N93 N95 D125 D127 N131 D182
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5szn, PDBe:5szn, PDBj:5szn
PDBsum5szn
PubMed27782885
UniProtQ91XX9

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