Structure of PDB 5ezm Chain A Binding Site BS13

Receptor Information
>5ezm Chain A (length=537) Species: 266264 (Cupriavidus metallidurans CH34) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAATGWVVLFVAVALVVWFVSLDMRHLVGPDEGRYAEISREMFASGDWVT
IRYNALKYFEKPPFHMWVTVVGYELFGLGEWQARLAVALSGLLGIGVSMM
AARRWFGARAAAFTGLALLAAPMWSVAAHFNTLDMTLAGVMSCVLAFMLM
GQHPDASVAARRGWMVACWAAMGVAILTKGLVGIALPGLVLVVYTLVTRD
WGLWRRLHLALGVVVMLVITVPWFYLVSVRNPEFPNFFFIHEHWQRRSGS
VFYFLPLVIGGFLPWAGIFPKLWTAMRARFRPALMAGIWAIAIFVFFSIS
RSKLPGYIVPVIPALGILAGVALDRLSPRSWGKQLIGMAIVAACGLLASP
VVATLNANHIPNSFYRAYAVWVAVAFVVMLLGIAVARLLLRRGVLPSVAV
YAMGMYLGFTVALLGHETVGRPASGADIAPQIAQKLTPEMPLYGVQMLDH
TLPFYLRHPLMMVGQADELTFGATVEPQRVVPDVDSFTKLWKNGQPAMAV
MSPDTYLALAPTLSMYVVARDWRRVVVANVASLAGPQ
Ligand information
Ligand IDPC
InChIInChI=1S/C5H14NO4P/c1-6(2,3)4-5-10-11(7,8)9/h4-5H2,1-3H3,(H-,7,8,9)/p+1
InChIKeyYHHSONZFOIEMCP-UHFFFAOYSA-O
SMILES
SoftwareSMILES
ACDLabs 10.04O=P(O)(O)OCC[N+](C)(C)C
CACTVS 3.341C[N+](C)(C)CCO[P](O)(O)=O
OpenEye OEToolkits 1.5.0C[N+](C)(C)CCOP(=O)(O)O
FormulaC5 H15 N O4 P
NamePHOSPHOCHOLINE
ChEMBLCHEMBL1235161
DrugBankDB03945
ZINCZINC000001532692
PDB chain5ezm Chain A Residue 655 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5ezm Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		L205 F262 H265
Binding residue
(residue number reindexed from 1)		L181 F238 H241
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.2.43: lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase.
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0010041 response to iron(III) ion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ezm, PDBe:5ezm, PDBj:5ezm
PDBsum5ezm
PubMed26912703
UniProtQ1LDT6

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