Structure of PDB 6e6b Chain B Binding Site BS12

Receptor Information
>6e6b Chain B (length=625) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QIRYKIPEEMPTGSVVGNLAKDLGFSVQELPTRKLRISSEKPYFSVSSES
GELLVSSRLDREQICGKKLMCALEFEAVAENPLNFYHLSVELEDINDHTP
KFAHTSFELQISESSKPGTRFILGSAHDADIGTNSLQNYQLSPNDHFSLV
NKEKSDGSKYPEMILKTALDREKQKLYHLTLTALDFGHPPLNSTAQIQVL
VTDANDNPPVFSQDIYRVSLPENVYPGTTVLRVVATDQDEGVNSEITFSF
SQFNLDSNTGEITTLHTLDFEEVKEYSLVLEAKDGGGMIAQCTVEIEVLD
ENDNVPEVLFQSLPDLIMEDAEPGTYIALLKTRDKDSGRNGEVICKLEGG
APFKILTSSGNTYKLVTDGVLDREQNPEYNITIRATDKGDPPLSSSSSVT
LHIGDVNDNAPVFTKVSYLVHVAENNPPGASIAQVSASDPDLGANGQVTY
YIIASDLEPESLWSYVTINAQSGVLFAQRAFDHEQLRSFQLTLQARDHGS
PTLSANVSMRLLVGDRNDNAPRVLYPTLEPDGSALFDMVPRSAEPGYLVT
KVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGDRDSAR
QRLLVAVRDGGQPPLSATATLHLIF
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6e6b Chain B Residue 712 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6e6b Visualization of clustered protocadherin neuronal self-recognition complexes.
Resolution4.52 Å
Binding residue
(original residue number in PDB)		N414 D446 D448 N452 D504
Binding residue
(residue number reindexed from 1)		N407 D439 D441 N445 D497
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6e6b, PDBe:6e6b, PDBj:6e6b
PDBsum6e6b
PubMed30971825
UniProtQ91XX6

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