Structure of PDB 5dzv Chain B Binding Site BS12

Receptor Information
>5dzv Chain B (length=522) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLHYSVPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNL
QNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDN
PPMFPATQKALFILESRLLDSRFPLEGASDADVGSNALLTYRLSTNEHFS
LDVPPNVKPLGLVLRKPLDREEAAEIRLLLTATDGGKPELTGTVQLLITV
LDVNDNAPVFDRSLYTVKLPENVPNGTLVIKVNASDLDEGVNGDVMYSFS
SDVSSDIKSKFHMDTVSGEITVIGIIDFEESKAYKIPLEARDKGFPQLPG
HCTILVEVVDANDNAPQLTVSSLSLPVSEDSQPGRVVTLISVFDRDSGAN
GQVTCSLTPHIPFKLVSTFKNYYSLVLDSALDRETIANYDVIVTARDGGS
PSLWATASVSVEVADVNDNAPLFAQPEYTVFVKENNPPGAHIFTVSAMDA
DAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHELLQFQV
SARDAGVPALGSNVTLQVFVLD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5dzv Chain B Residue 611 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5dzv Structural Basis of Diverse Homophilic Recognition by Clustered alpha- and beta-Protocadherins.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		E332 D385 E387 D421
Binding residue
(residue number reindexed from 1)		E329 D382 E384 D418
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5dzv, PDBe:5dzv, PDBj:5dzv
PDBsum5dzv
PubMed27161523
UniProtQ91Y13|PCDA7_MOUSE Protocadherin alpha-7 (Gene Name=Pcdha7)

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