Structure of PDB 3bcd Chain A Binding Site BS12

Receptor Information
>3bcd Chain A (length=585) Species: 373903 (Halothermothrix orenii H 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLFLIESEPSTGASVSKNLTEIILIFSNDINKVSQLALTDLITDSDIQGI
DYNIEGNKVIINNFSLEPTCNYRLSYEVIDIYDNHLQGYIEFLVNQSNYP
QIPDQEVNHTILQAFYWEMNTGEYATEHPEEANLWNLLAERAPELAEAGF
TAVWLPPANKGMAGIHDVGYGTYDLWDLGEFDQKGTVRTKYGTKGELENA
IDALHNNDIKVYFDAVLNHRMGADYAETVLLDENSRDKPGQYIKAWTGFN
FPGRNGEYSNFTWNGQCFDGTDWDDYSKESGKYLFDEKSWDWTYNWDEDY
LMGADVDYENEAVQNDVIDWGQWIINNIDFDGFRLDAVKHIDYRFIDKWM
SAVQNSSNRDVFFVGEAWVEDVDDLKGFLDTVGNPDLRVFDFPLRSFFVD
MLNGAYMADLRNAGLVNSPGYENRAVTFVDNHDTDRDEGSYTVSIYSRKY
QAYAYILTRAEGVPTVYWKDYYIWEMKEGLDKLLTARRYYAYGPGYEVDN
NDADIYSYVRSGFPDVAGDGLVLMISDGTSGNVAGKWINSRQPDTEFYDL
TGHIKEHVTTDSEGYGNFKVIKSEDKGWSIWVPVE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3bcd Chain A Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3bcd Crystal Structure of the Polyextremophilic alpha-Amylase AmyB from Halothermothrix orenii: Details of a Productive Enzyme-Substrate Complex and an N Domain with a Role in Binding Raw Starch
Resolution2.2 Å
Binding residue
(original residue number in PDB)		A419 A517 D518 D541
Binding residue
(residue number reindexed from 1)		A405 A503 D504 D527
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) D350 E380 D447
Catalytic site (residue number reindexed from 1) D336 E366 D433
Enzyme Commision number 3.2.1.98: glucan 1,4-alpha-maltohexaosidase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0033927 glucan 1,4-alpha-maltohexaosidase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3bcd, PDBe:3bcd, PDBj:3bcd
PDBsum3bcd
PubMed18387632
UniProtB8CZ54

[Back to BioLiP]