Structure of PDB 2z8z Chain A Binding Site BS12

Receptor Information
>2z8z Chain A (length=616) Species: 91465 (Pseudomonas sp. MIS38) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVYDYKNFGTADSKALFSDAMAITLYSYHNLDNGFAAGYQHNGFGLGLPA
TLVTALLGGTDSQGVIPGIPWNPDSEKLALDAVKKAGWTPITASQLGYDG
KTDARGTFFGEKAGYTTAQVEILGKYDAQGHLTEIGIAFRGTSGPRENLI
LDSIGDVINDLLAAFGPKDYAKNYVGEAFGNLLNDVVAFAKANGLSGKDV
LVSGHSLGGLAVNSMADLSGGKWGGFFADSNYIAYASPTQSSTDKVLNVG
YENDPVFRALDGSTFTGASVGVHDAPKESATDNIVSFNDHYASTAWNLLP
FSILNIPTWISHLPTAYGDGMNRIIESKFYDLTSKDSTIIVANLSDPARA
NTWVQDLNRNAETHKGSTFIIGSDSNDLIQGGSGNDYLEGRAGNDTFRDG
GGYNVILGGAGNNTLDLQKSVNTFDFANDGAGNLYVRDANGGICITRDIG
SIVTKEPGFLWGLFKDDVTHSVTASGLKVGSNVTQYDASVKGTNGADTLK
AHAGGDWLFGLDGNDHLIGGVGNDVFVGGAGNDLMESGGGADTFLFNGAF
GQDRVVGFTSNDKLVFLGVQGVLPNDDFRAHASMVGQDTVLKFGGDSVTL
VGVALNSLSADGIVIA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2z8z Chain A Residue 629 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2z8z Crystal structure of a family I.3 lipase from Pseudomonas sp. MIS38 in a closed conformation
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D128 H132
Binding residue
(residue number reindexed from 1)		D127 H131
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.3: triacylglycerol lipase.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:2z8z, PDBe:2z8z, PDBj:2z8z
PDBsum2z8z
PubMed17923123
UniProtQ9RBY1

[Back to BioLiP]