Structure of PDB 5dzy Chain D Binding Site BS11

Receptor Information
>5dzy Chain D (length=412) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AISYSMPEETESGYLVANLAQDLGLRVGELTTRGARIHHNGNKELLQLDA
ERGNLLLKEKPDREALCGATEPCVLHFQIILENPVQFFQTDLQFTDINDH
FPEFPDTEMLLKIQEIAQPGTVFPLKAAQDPDIGSNAVQNYTVSPNLHFH
VVTLSRSDDRKYPELVLDRALDREEQPELTLILTALDGGAPPKSGTTTVR
IEVVDINDNAPQFLQSLYAVEVPENSPLNALVVTVSARDLDAGIHGNVAY
SLFQGGGGPQPFVIDEITGEIRLKGALDFEATSYYTMEIVATDSGGLSGK
CTVAIQVLDVNDNAPKLTISSLTSSIPENAPEAVVAVFSVSDPDSGDNGR
MVCSIQNGLPFLLKPTFKNFYTLVTERPLDRESNAEYNITITVSDLGTPR
LTTQHTITVQVS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5dzy Chain D Residue 514 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5dzy Structural Basis of Diverse Homophilic Recognition by Clustered alpha- and beta-Protocadherins.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		N312 N314 D343 D345 N349 D396
Binding residue
(residue number reindexed from 1)		N311 N313 D342 D344 N348 D395
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5dzy, PDBe:5dzy, PDBj:5dzy
PDBsum5dzy
PubMed27161523
UniProtQ91XZ2|PCDB8_MOUSE Protocadherin beta-8 (Gene Name=Pcdhb8)

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