Structure of PDB 5dzv Chain B Binding Site BS11

Receptor Information
>5dzv Chain B (length=522) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLHYSVPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNL
QNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDN
PPMFPATQKALFILESRLLDSRFPLEGASDADVGSNALLTYRLSTNEHFS
LDVPPNVKPLGLVLRKPLDREEAAEIRLLLTATDGGKPELTGTVQLLITV
LDVNDNAPVFDRSLYTVKLPENVPNGTLVIKVNASDLDEGVNGDVMYSFS
SDVSSDIKSKFHMDTVSGEITVIGIIDFEESKAYKIPLEARDKGFPQLPG
HCTILVEVVDANDNAPQLTVSSLSLPVSEDSQPGRVVTLISVFDRDSGAN
GQVTCSLTPHIPFKLVSTFKNYYSLVLDSALDRETIANYDVIVTARDGGS
PSLWATASVSVEVADVNDNAPLFAQPEYTVFVKENNPPGAHIFTVSAMDA
DAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHELLQFQV
SARDAGVPALGSNVTLQVFVLD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5dzv Chain B Residue 610 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5dzv Structural Basis of Diverse Homophilic Recognition by Clustered alpha- and beta-Protocadherins.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		E332 E387 D418 V419 D421 D454
Binding residue
(residue number reindexed from 1)		E329 E384 D415 V416 D418 D451
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5dzv, PDBe:5dzv, PDBj:5dzv
PDBsum5dzv
PubMed27161523
UniProtQ91Y13|PCDA7_MOUSE Protocadherin alpha-7 (Gene Name=Pcdha7)

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