Structure of PDB 8ssq Chain A Binding Site BS11

Receptor Information
>8ssq Chain A (length=260) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYASVEVSKLKR
HIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQ
SGTMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKK
CRYCDAVFHERYALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHT
GEKPYACSHCDKTFRQKQLLDMHFKRYHDPNFVPAAFVCSKCGKTFTRRN
TMARHADNCA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8ssq Chain A Residue 709 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ssq Structures of CTCF-DNA complexes including all 11 zinc fingers.
Resolution3.12 Å
Binding residue
(original residue number in PDB)		C557 C560 H573 C577
Binding residue
(residue number reindexed from 1)		C239 C242 H255 C259
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8ssq, PDBe:8ssq, PDBj:8ssq
PDBsum8ssq
PubMed37439339
UniProtP49711|CTCF_HUMAN Transcriptional repressor CTCF (Gene Name=CTCF)

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