Structure of PDB 5yjg Chain A Binding Site BS11

Receptor Information

>5yjg Chain A (length=594) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRME
GMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAP
SNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPS
MYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSI
QDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVL
ERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDS
ITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDL
VAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVK
VGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHI
FREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPT
NDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKT
TQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

5yjg Chain A Residue 732 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5yjg Structural characterizations of human periostin dimerization and cysteinylation.
Resolution	2.399 Å
Binding residue (original residue number in PDB)	F195 N197 T205 N207 C208
Binding residue (residue number reindexed from 1)	F158 N160 T168 N170 C171
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:5yjg, PDBe:5yjg, PDBj:5yjg
PDBsum	5yjg
PubMed	29754429
UniProt	Q15063\|POSTN_HUMAN Periostin (Gene Name=POSTN)

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