Structure of PDB 2w6d Chain B Binding Site BS10

Receptor Information
>2w6d Chain B (length=680) Species: 63737 (Nostoc punctiforme PCC 73102) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VNQVATDRFIQDLERVAQVRSEMSVCLNKLAETINKAELAGDSSSGKLSL
ERDIEDITIASKNLQQGVFRLLVLGDMKRGKSTFLNALIGENLLPSTAVL
TVLRYGPEKKVTIHFNDGKSPQQLDFQNFKYKYTIDPAEAKKLEQEKKQA
FPDVDYAVVEYPLTLLQKGIEIVDSPGLNDTEARNELSLGYVNNCHAILF
VMRASQPCTLGERRYLENYIKGRGLTVFFLVNAWDQVRESLIDPDDVEEL
QASENRLRQVFNANLAEYCTVEGQNIYDERVFELSSIQALRRRLKNPQAD
LDGTGFPKFMDSLNTFLTRERAIAELRQVRTLARLACNHTREAVARRIPL
LEQDVNELKKRIDSVEPEFNKLTGIRDEFQKEIINTRDTQARTISESFRS
YVLNLGNTFENDFLRYQPELNLFDFLSSGKREAFNAALQKAFEQYITDKS
AAWTLTAEKDINAAFKELSRSASQYGASYNQITDQITEKLTGKDVEDNSP
GWAKWAMGLLSLSKGNLAGFALAGAGFDWKNILLNYFTVIGIGGIITAVT
GILLGPIGFALLGLGVGFLQADQARRELVKTAKKELVKHLPQVAHEQSQV
VYNAVKECFDSYEREVSKRINDDIVSRKSELDNLVKQKQTREINRESEFN
RLKNLQEDVIAQLQKIEAAYSNLLAYYSHH
Ligand information
Ligand IDCPL
InChIInChI=1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
InChIKeyJLPULHDHAOZNQI-ZTIMHPMXSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(OCC(OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COP([O-])(=O)OCC[N+](C)(C)C)CCCCCCCCCCCCCCC
OpenEye OEToolkits 1.5.0CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCC=CCCCCC
CACTVS 3.341CCCCCCCCCCCCCCCC(=O)OC[CH](CO[P]([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCC=CCCCCC
CACTVS 3.341CCCCCCCCCCCCCCCC(=O)OC[C@H](CO[P]([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C/C=C\CCCCC
OpenEye OEToolkits 1.5.0CCCCCCCCCCCCCCCC(=O)OC[C@H](CO[P@@](=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC
FormulaC42 H80 N O8 P
Name1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;
PALMITOYL-LINOLEOYL PHOSPHATIDYLCHOLINE
ChEMBL
DrugBankDB02306
ZINC
PDB chain2w6d Chain B Residue 1704 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2w6d Structure of a Bacterial Dynamin-Like Protein Lipid Tube Provides a Mechanism for Assembly and Membrane Curving.
Resolution9.0 Å
Binding residue
(original residue number in PDB)		G412 N413 T414 F415 E416 D587 R590
Binding residue
(residue number reindexed from 1)		G406 N407 T408 F409 E410 D572 R575
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.5: dynamin GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008289 lipid binding
GO:0016787 hydrolase activity
GO:0042802 identical protein binding
Biological Process
GO:0008053 mitochondrial fusion
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2w6d, PDBe:2w6d, PDBj:2w6d
PDBsum2w6d
PubMed20064379
UniProtB2IZD3|BDLP_NOSP7 Bacterial dynamin-like protein (Gene Name=Npun_R6513)

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