Structure of PDB 5szq Chain A Binding Site BS10

Receptor Information
>5szq Chain A (length=422) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NAPVFTQPEYHISVKENLPVGTRLLTIKATDPDEGEVTYSFRNVREKISQ
LFQLNSLTGDITVLGELDYEDSGFYDVDVEAHDGPGLRARSKVLVTVLDV
NDNAPEVTVTSLTSSIQEASSPGTVIALFNVHDSDSGENGLVTCSIPDNL
PFRLEKTYGNYHRLLIHRTLDREEVSDYNITITATDQGTPPLSTETYISL
QVVDINDNPPTFTHASYSAYIPENNPRGASILSITAQDPDSGENAQVIYS
LSEDTIQGAPMSSYVSINSNTGVLYALRSFDYEQFQDLKLLVTARDSGTP
PLSSNVSLSLSVLDQNDNTPEILYPTISTGVELTPRSADPGYLVTKVVAV
DKDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVV
TVQDHGQPPLSATVTLTIAVSD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5szq Chain A Residue 715 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5szq gamma-Protocadherin structural diversity and functional implications.
Resolution2.608 Å
Binding residue
(original residue number in PDB)		N418 N420 D450 D452 N456 D508
Binding residue
(residue number reindexed from 1)		N206 N208 D238 D240 N244 D296
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5szq, PDBe:5szq, PDBj:5szq
PDBsum5szq
PubMed27782885
UniProtQ91XY4|PCDG4_MOUSE Protocadherin gamma-A4 (Gene Name=Pcdhga4)

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