Structure of PDB 2zj6 Chain A Binding Site BS10

Receptor Information
>2zj6 Chain A (length=616) Species: 91465 (Pseudomonas sp. MIS38) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVYDYKNFGTADSKALFSDAMAITLYSYHNLDNGFAAGYQHNGFGLGLPA
TLVTALLGGTDSQGVIPGIPWNPDSEKLALDAVKKAGWTPITASQLGYDG
KTDARGTFFGEKAGYTTAQVEILGKYDAQGHLTEIGIAFRGTSGPRENLI
LDSIGDVINDLLAAFGPKDYAKNYVGEAFGNLLNDVVAFAKANGLSGKDV
LVSGHSLGGLAVNSMADLSGGKWGGFFADSNYIAYASPTQSSTDKVLNVG
YENDPVFRALDGSTFTGASVGVHDAPKESATDNIVSFNDHYASTAWNLLP
FSILNIPTWISHLPTAYGDGMNRIIESKFYDLTSKASTIIVANLSDPARA
NTWVQDLNRNAETHKGSTFIIGSDSNDLIQGGSGNDYLEGRAGNDTFRDG
GGYNVILGGAGNNTLDLQKSVNTFDFANDGAGNLYVRDANGGISITRDIG
SIVTKEPGFLWGLFKDDVTHSVTASGLKVGSNVTQYDASVKGTNGADTLK
AHAGGDWLFGLDGNDHLIGGVGNDVFVGGAGNDLMESGGGADTFLFNGAF
GQDRVVGFTSNDKLVFLGVQGVLPNDDFRAHASMVGQDTVLKFGGDSVTL
VGVALNSLSADGIVIA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2zj6 Chain A Residue 627 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2zj6 Importance of the Ca2+-binding sites in the N-catalytic domain of a family I.3 lipase for activity and stability
Resolution2.25 Å
Binding residue
(original residue number in PDB)		D128 H132
Binding residue
(residue number reindexed from 1)		D127 H131
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.3: triacylglycerol lipase.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:2zj6, PDBe:2zj6, PDBj:2zj6
PDBsum2zj6
PubMed18987131
UniProtQ9RBY1

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