Structure of PDB 1l3w Chain A Binding Site BS09

Receptor Information
>1l3w Chain A (length=540) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DWVIPPIKVSENERGPFPKRLVQIKSNKDRFNKVYYSITGQGADNPPQGV
FRIEWETGWMLVTRPLDREEYDKYVLSSHAVSENGSPVEEPMEITINVID
QNDNRPKFTQDVFRGSVREGVQPGTQVMAVSATDEDDNIDSLNGVLSYSI
LKQDPEEPIPNLFTINRETGVISLIGTGLDREKFPEYTLTVQATDLEGAG
LSVEGKAIIQITDANDNAPIFDPKTYTALVPENEIGFEVQRLSVTDLDMP
GTPAWQAVYKIRVNEGGFFNITTDPESNQGILTTAKGLDFELRKQYVLQI
TVENAEPFSVPLPTSTATVTVTVEDVNEAPFFVPAVSRVDVSEDLSRGEK
IISLVAQDPDKQQIQKLSYFIGNDPARWLTVNKDNGIVTGNGNLDRESEY
VKNNTYTVIMLVTDDGVSVGTGTGTLILHVLDVNDNGPVPSPRVFTMCDQ
NPEPQVLTISDADIPPNTYPYKVSLSHGSDLTWKAELDSKGTSMLLSPTQ
QLKKGDYSIYVLLSDAQNNPQLTVVNATVCSCEGKAIKCQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1l3w Chain A Residue 608 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1l3w C-cadherin ectodomain structure and implications for cell adhesion mechanisms
Resolution3.08 Å
Binding residue
(original residue number in PDB)		E343 D395 E397 D435
Binding residue
(residue number reindexed from 1)		E343 D395 E397 D435
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1l3w, PDBe:1l3w, PDBj:1l3w
PDBsum1l3w
PubMed11964443
UniProtP33148|CADHF_XENLA EP-cadherin

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