Structure of PDB 3cmt Chain D Binding Site BS08

Receptor Information
>3cmt Chain D (length=1609) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQRE
GKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSG
AVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSN
TLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGEN
VVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEK
AGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSAID
ENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGA
GGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIY
ARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKA
EIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMF
GNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAA
PFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKA
NATAWLKDNPETAKEIEKKVRELLLSNPNSAIDENKQKALAAALGQIEKQ
FGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESS
GKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPD
TGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARM
MSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYAS
VRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINF
YGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIE
KKVRELLLSNPNSAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDV
ETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREG
KTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGA
VDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNT
LLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENV
VGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKA
GAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSAIDE
NKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAG
GLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYA
RKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAE
MGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKNPETTTGGNALKFYA
SVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGIN
FYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEI
EKKVRELLL
Ligand information
Ligand IDALF
InChIInChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4
InChIKeyUYOMQIYKOOHAMK-UHFFFAOYSA-J
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al-](F)(F)F
FormulaAl F4
NameTETRAFLUOROALUMINATE ION
ChEMBL
DrugBankDB04444
ZINC
PDB chain3cmt Chain D Residue 2501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3cmt Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Resolution3.15 Å
Binding residue
(original residue number in PDB)		E2068 S2069 K2072 E2096 F3217 K3248 K3250
Binding residue
(residue number reindexed from 1)		E698 S699 K702 E726 F1180 K1211 K1213
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity
GO:0140297 DNA-binding transcription factor binding
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0000725 recombinational repair
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006974 DNA damage response
GO:0009432 SOS response
GO:0010212 response to ionizing radiation
GO:0019985 translesion synthesis
GO:0035825 homologous recombination
GO:0048870 cell motility
Cellular Component
GO:0005737 cytoplasm
GO:0009355 DNA polymerase V complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3cmt, PDBe:3cmt, PDBj:3cmt
PDBsum3cmt
PubMed18497818
UniProtP0A7G6|RECA_ECOLI Protein RecA (Gene Name=recA)

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