Structure of PDB 7whf Chain C Binding Site BS08

Receptor Information
>7whf Chain C (length=225) Species: 1841598 (Candidatus Heimdallarchaeota archaeon LC_3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVKVLHVQGKKLKEVQSPYNFLNGDVYVIDDSKKPDGSDKDPVDSPKVYI
WLGSKAYADDRGVGAWAAKMLDKENQAIDIDTEVEGKESAEFKTIVDFSV
VEGDTPGFLKHVEVNFQDVDYEMYRVYDTDLSDGSSSDDIEIDPVPLSKN
SLKSEDVFVIDGWNDIYVWIGSKSQVGEKAAGNRLARKLDTERKRTPMVY
TVNEGLEPNGFFEFLEKLEQEDPKK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7whf Chain C Residue 308 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7whf Structural and biochemical evidence for the emergence of a calcium-regulated actin cytoskeleton prior to eukaryogenesis
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D79 D81
Binding residue
(residue number reindexed from 1)		D79 D81
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0046872 metal ion binding
GO:0051015 actin filament binding
Biological Process
GO:0051014 actin filament severing
GO:0051016 barbed-end actin filament capping

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:7whf, PDBe:7whf, PDBj:7whf
PDBsum7whf
PubMed
UniProtA0A1Q9NVH4

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