Structure of PDB 1sum Chain B Binding Site BS08

Receptor Information

>1sum Chain B (length=225) Species: 2336 (Thermotoga maritima)

NRLLNEKVEEFKKGVLKAGWFIEKMFRNSISSLVERNESLAREVIADEEV
VDQMEVEIQEKAMEVLGLFSPIGKPLLTVTAGIRVAELIENIADKCHDIA
KNVLELMEEPPLKPLEDIPAMANQTSEMLKFALRMFADVNVEKSFEVCRM
DSKVDDLYEKVREELLLYMMESPKYVKRALLLLEIAGNIEIIADYATNIV
EVSVYMVQGEAYKCYHDELLLFKKS

Ligand information

• Ligand ID: PO3
• InChI: InChI=1S/O3P/c1-4(2)3/q-3
• InChIKey: AQSJGOWTSHOLKH-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [O-][P-]([O-])=O
  ACDLabs 10.04: [O-][PH2-]([O-])=O
  OpenEye OEToolkits 1.5.0: [O-][P-](=O)[O-]
• Formula: O3 P
• Name: PHOSPHITE ION
• PDB chain: 1sum Chain B Residue 568

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1sum Crystal structure of a PhoU protein homologue: a new class of metalloprotein containing multinuclear iron clusters.
• Resolution: 2.0 Å
• Binding residue (original residue number in PDB): D156 D195
• Binding residue (residue number reindexed from 1): D155 D194
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0042803 protein homodimerization activity

Biological Process

• GO:0006817 phosphate ion transport
• GO:0030643 intracellular phosphate ion homeostasis
• GO:0045936 negative regulation of phosphate metabolic process
• GO:2000186 negative regulation of phosphate transmembrane transport

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:1sum, PDBe:1sum, PDBj:1sum
• PDBsum: 1sum
• PubMed: 15716271
• UniProt: Q9X256|PHOU2_THEMA Phosphate-specific transport system accessory protein PhoU homolog 2 (Gene Name=phoU2)