Structure of PDB 7rgf Chain A Binding Site BS08

Receptor Information

>7rgf Chain A (length=418) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QIRYPVPEESQEGTFVGNVAQDFLLDTESLSARRLQVAGEVNQRHFRVDL
DSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDH
APRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFA
LDVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELR
VSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTF
SFSGHTPDRVRNLFSLHPTTGKLTLQGPLDFESENYYEFDVRARDGGSPA
MEQHCSLRVDLLDVNDNAPHITVTSELGTLPESAEPGTVVALISVQDPDS
GSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREARSSYDIMVTASD
AGNPPLSTHRTIFLNISD

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

7rgf Chain A Residue 511 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7rgf How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition.
Resolution	2.4 Å
Binding residue (original residue number in PDB)	E224 D280 E282 D316
Binding residue (residue number reindexed from 1)	E224 D280 E282 D316
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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Cellular Component

External links

PDB	RCSB:7rgf, PDBe:7rgf, PDBj:7rgf
PDBsum	7rgf
PubMed	35253643
UniProt	Q91XX0

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