Structure of PDB 5t9t Chain A Binding Site BS08

Receptor Information

>5t9t Chain A (length=526) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DQIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPE
SGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNA
PLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEV
TEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRI
QVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYA
FHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASH
CSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENG
DVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKP
PLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPD
LGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQL
TLQARDHGSPTLSANVSMRVLVGDRN

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

5t9t Chain A Residue 608 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	5t9t gamma-Protocadherin structural diversity and functional implications.
Resolution	3.5 Å
Binding residue (original residue number in PDB)	E223 E280 D309 E310 D312 D345
Binding residue (residue number reindexed from 1)	E223 E280 D309 E310 D312 D345
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:5t9t, PDBe:5t9t, PDBj:5t9t
PDBsum	5t9t
PubMed	27782885
UniProt	Q8K486

[Back to BioLiP]