Structure of PDB 7msh Chain x Binding Site BS07

Receptor Information
>7msh Chain x (length=550) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRIMA
GLDKPNNGDAFLATGATVGILQQEPPLNEDKTVRGNVEEGMGDIKIKLDR
FNEVAELMATDYTDELMEEMGRLQEELDHADAWDLDAQLEQAMDALRCPP
ADEPVTNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQHL
ASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAERL
AVQGRKDAKLQKRLTEELAWVRSGAKARQAKSKARLQRYEEMAAEAEKTR
KLDFEEIQIPVGPRLGNVVVEVDHLDKGYDGRALIKDLSFSLPRNGIVGV
IGPNGVGKTTLFKTIVGLETPDSGSVKVGETVKLSYVDQARAGIDPRKTV
WEVVSDGLDYIQVGQTEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNRLN
LALTLKQGGNLILLDEPTNDLDVETLGSLENALLNFPGCAVVISHDRWFL
DRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKVERLGVDVTHRKLTRG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7msh Chain x Residue 604 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7msh Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Resolution3.23 Å
Binding residue
(original residue number in PDB)		T361 Q391
Binding residue
(residue number reindexed from 1)		T359 Q389
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.1.-
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0019843 rRNA binding
GO:0043022 ribosome binding
Biological Process
GO:0006412 translation
GO:0006417 regulation of translation
GO:0045900 negative regulation of translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7msh, PDBe:7msh, PDBj:7msh
PDBsum7msh
PubMed35064151
UniProtP9WQK3|ETTA_MYCTU Energy-dependent translational throttle protein EttA (Gene Name=ettA)

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