Structure of PDB 6s91 Chain K Binding Site BS07

Receptor Information

>6s91 Chain K (length=1023) Species: 930945 (Sulfolobus islandicus REY15A)

EFLDYKIIALLHDPPNKAWVITGRARNLTQQLSRKHEKVAKYIINQLFGK
NYSEKVDNADKLASSIDRYLGSIVYKERSLFENRSIFLKNILLSNIQRDI
GNLFPKDKSKLDNLILEYKKLLNVINKTNLILKYQLFYLIYELVWIDSKY
ENTPSDTRNPTHTIFDHLYATAAMMNWILSLEKEAKGYLLGIDTIGVADF
ISKGRKTRDLWISSYLVSALLWYVITWFIEEYGPDVILFPSLRFNQFYAF
YLLEKLRKEGVSEDVIDEIKELITKYIFNGDDLFENLKIPPYPIIPGRIT
LILPGLIREGEEYKKVQDDNCFISKVKERYNEGWRKLIEGLRCYSERKRE
DGFWNLVCRVLKLTEDLLQTTPLNIRVKQVSVTEDEIFNNNKLRSDSWKI
YDNKYRQLVSEFKKSKLVKVTPESRLKLFELTKFDKLPQIGEKSKRGYEF
CTSCGVLPAVVIMPKEDELEKKLIDLGIARDEKDVRSIKNMISPGERLCP
WCLVKRALGAEPRLMRILLLGDLYSVEKIVNEIVSRDVKIEIPSTSDIAS
IKTFEEMIEKKNEICEDLKEEEVCEKPSESVLSMWQWFNKNYYNGINLTI
DPEEYWFSEKRRRYYFSVFRRHRITFPSPYYALVRADSDYLGDLLEGKLT
PYLAGIIDSGDYANISEKKEEVNKLLEEYLVNAGSGSIVDYVKTVLKCIR
ENLNKCSCAEKIYSNEVAKVMFRVNVEKANVEEEVKNSLEYFETILNEGR
IIVTPAWHVSISSALNRGLLVELELVNKHKGFVIYAGGDDLLAMLPVDEV
LDFIKESRRAFAGFGTEKLGNMCLENGFVRINNAYYPSLPIVGRSYSVII
AHYADPLFFVINDSYNLLEEGKEIIRYRVMYNGEYKDAKKDVAIFRYQGL
TSVIPLSLKRPIVSSVSDFNEIASIIDVILELKKRIDEGRISVSLLYDYE
KYKHLIVASDEKYLTEFLVKDWIKRNSLRKHVEFTIDEKLYGVRLTIENY
PIKIPNDLISNIVYTLRIIYGGE

Ligand information

• Ligand ID: MN
• InChI: InChI=1S/Mn/q+2
• InChIKey: WAEMQWOKJMHJLA-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mn+2]
  CACTVS 3.341: [Mn++]
• Formula: Mn
• Name: MANGANESE (II) ION
• DrugBank: DB06757
• PDB chain: 6s91 Chain K Residue 1106

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6s91 Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
• Resolution: 2.68 Å
• Binding residue (original residue number in PDB): D206 T207 I208
• Binding residue (residue number reindexed from 1): D193 T194 I195
• Annotation score: 4

Gene Ontology

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:6s91, PDBe:6s91, PDBj:6s91
• PDBsum: 6s91
• PubMed: 32730741
• UniProt: F0NDX2