Structure of PDB 6vfu Chain C Binding Site BS07

Receptor Information
>6vfu Chain C (length=428) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNSAPHL
VDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKD
LNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPN
ELFGLEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGT
VGLSIKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNG
QVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDL
GPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALV
RVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNL
TIQARDGGVPMLQSAKSFTVLITDHHHH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6vfu Chain C Residue 507 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6vfu Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
E228 E286 D317 T318 D320 D356
Binding residue
(residue number reindexed from 1)
E228 E286 D317 T318 D320 D356
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6vfu, PDBe:6vfu, PDBj:6vfu
PDBsum6vfu
PubMed32101743
UniProtQ8TAB3|PCD19_HUMAN Protocadherin-19 (Gene Name=PCDH19)

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