Structure of PDB 6eet Chain A Binding Site BS07

Receptor Information
>6eet Chain A (length=443) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDD
VQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSS
ATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIVY
SIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANL
RVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKAT
DRDTGNYSAMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFK
FQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLVEKKIEDLTE
ILDRYVQEQIPGAKVVVESIGARRHGDAYSLEDYSKCDLTVYAIDPQTNR
AIDRNELFKFLDGKLLDINKDFQPYYGEGGRILEIRTPEAVTS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6eet Chain A Residue 1412 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6eet Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
Resolution3.23 Å
Binding residue
(original residue number in PDB)		N899 Y901 D931 D933 A939 D989
Binding residue
(residue number reindexed from 1)		N1 Y3 D33 D35 A41 D91
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6eet, PDBe:6eet, PDBj:6eet
PDBsum6eet
PubMed32963095
UniProtQ99PJ1|PCD15_MOUSE Protocadherin-15 (Gene Name=Pcdh15)

[Back to BioLiP]