Structure of PDB 4nxc Chain A Binding Site BS07

Receptor Information
>4nxc Chain A (length=153) Species: 9755 (Physeter catodon) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLK
TEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIP
IKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELG
YQG
Ligand information
Ligand IDN2O
InChIInChI=1S/N2O/c1-2-3
InChIKeyGQPLMRYTRLFLPF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341		[O-][N+]#N
OpenEye OEToolkits 1.5.0N#[N+][O-]
FormulaN2 O
NameNITROUS OXIDE;
NITROGEN OXIDE
ChEMBLCHEMBL1234579
DrugBankDB06690
ZINC
PDB chain4nxc Chain A Residue 210 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4nxc Crystallographic Studies with Xenon and Nitrous Oxide Provide Evidence for Protein-dependent Processes in the Mechanisms of General Anesthesia
Resolution1.55 Å
Binding residue
(original residue number in PDB)		I28 L29 G65 V68 L69
Binding residue
(residue number reindexed from 1)		I28 L29 G65 V68 L69
Annotation score1
Enzymatic activity
Enzyme Commision number 1.11.1.-
1.7.-.-
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0005344 oxygen carrier activity
GO:0016491 oxidoreductase activity
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0098809 nitrite reductase activity
Biological Process
GO:0015671 oxygen transport
GO:0019430 removal of superoxide radicals
Cellular Component
GO:0005737 cytoplasm
GO:0016528 sarcoplasm
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4nxc, PDBe:4nxc, PDBj:4nxc
PDBsum4nxc
PubMed25211169
UniProtP02185|MYG_PHYMC Myoglobin (Gene Name=MB)

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