Structure of PDB 3wdr Chain A Binding Site BS07

Receptor Information

>3wdr Chain A (length=330) Species: 356864 (Symbiotic protist of Reticulitermes speratus)

QDWNISSSPVTPSPSAGAQKLYSFLVQNFQKKIISGAMTLQGGDESAQTK
EPDWLQQNAGHRPALVGLDFMFQTGKGEEWYYNDSRFSKQVVNGAKSYWQ
KGGIPALCWHWRDPSKDTDAFYSPSSGNSATQFDADQAVKSGTAENKAIL
QDLAVIADQLQDLRDAGVAVLWRPLHEASGKWFWWGYKGADALKKLWKIE
FDYFVKERNLNNLIWVFTAGTPIEGIADWYPGDDMVDVIGMDIYATQGDH
ATQQDYFNQCKSIFKGRKIVAMSECGSVPEPDLAAPWSFFMPWYNNYCIP
EGSNPYNSLEFWKKTMSSSLVITLDNMPGW

Ligand information

• Ligand ID: BCT
• InChI: InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1
• InChIKey: BVKZGUZCCUSVTD-UHFFFAOYSA-M
• SMILES:
  OpenEye OEToolkits 1.5.0: C(=O)(O)[O-]
  CACTVS 3.341: OC([O-])=O
  ACDLabs 10.04: [O-]C(=O)O
• Formula: C H O3
• Name: BICARBONATE ION
• PDB chain: 3wdr Chain A Residue 404

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3wdr Structural and Biochemical Analyses of Glycoside Hydrolase Family 26 beta-Mannanase from a Symbiotic Protist of the Termite Reticulitermes speratus
• Resolution: 1.4 Å
• Binding residue (original residue number in PDB): H124 H190 E288
• Binding residue (residue number reindexed from 1): H110 H176 E274
• Annotation score: 4

Enzymatic activity

• Enzyme Commision number: 3.2.1.78: mannan endo-1,4-beta-mannosidase.

Gene Ontology

Molecular Function

• GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
• GO:0016787 hydrolase activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0016985 mannan endo-1,4-beta-mannosidase activity

Biological Process

• GO:0006080 substituted mannan metabolic process

External links

• PDB: RCSB:3wdr, PDBe:3wdr, PDBj:3wdr
• PDBsum: 3wdr
• PubMed: 24570006
• UniProt: H7CGE2