Structure of PDB 3ubf Chain A Binding Site BS07

Receptor Information
>3ubf Chain A (length=298) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAVRPTKRIEFTEADGDTEGKSVFQLEKETDKETFKIRDDNPWVTVETNG
AVRVKKKWDYEELGPEKTIDFWVIITNKYTDNQRVIILVKDVNDEPPYFI
NRPLPMQAVVQLNAPPNTPVFTLQARDPDTDHNIHYFIVRDRTGGRFEVD
ERSGVVRTRGTDLFQLDMEYVLYVKAEDQNGQSTPEERLSIVGGKRAPQF
YMPSYEAEIPENQKKDSDIISIKAKSFADREIRYTLKAQGQGAGTFNIGP
TSGIVKLAKELDFEDLRQPHVYSLIVTATEDSGGFSTSVDLTIRVTDV
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3ubf Chain A Residue 754 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3ubf Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkers.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		E450 D496 E498 D575
Binding residue
(residue number reindexed from 1)		E13 D59 E61 D131
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3ubf, PDBe:3ubf, PDBj:3ubf
PDBsum3ubf
PubMed22171007
UniProtO15943|CADN_DROME Neural-cadherin (Gene Name=CadN)

[Back to BioLiP]