Structure of PDB 2zj6 Chain A Binding Site BS07

Receptor Information
>2zj6 Chain A (length=616) Species: 91465 (Pseudomonas sp. MIS38) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVYDYKNFGTADSKALFSDAMAITLYSYHNLDNGFAAGYQHNGFGLGLPA
TLVTALLGGTDSQGVIPGIPWNPDSEKLALDAVKKAGWTPITASQLGYDG
KTDARGTFFGEKAGYTTAQVEILGKYDAQGHLTEIGIAFRGTSGPRENLI
LDSIGDVINDLLAAFGPKDYAKNYVGEAFGNLLNDVVAFAKANGLSGKDV
LVSGHSLGGLAVNSMADLSGGKWGGFFADSNYIAYASPTQSSTDKVLNVG
YENDPVFRALDGSTFTGASVGVHDAPKESATDNIVSFNDHYASTAWNLLP
FSILNIPTWISHLPTAYGDGMNRIIESKFYDLTSKASTIIVANLSDPARA
NTWVQDLNRNAETHKGSTFIIGSDSNDLIQGGSGNDYLEGRAGNDTFRDG
GGYNVILGGAGNNTLDLQKSVNTFDFANDGAGNLYVRDANGGISITRDIG
SIVTKEPGFLWGLFKDDVTHSVTASGLKVGSNVTQYDASVKGTNGADTLK
AHAGGDWLFGLDGNDHLIGGVGNDVFVGGAGNDLMESGGGADTFLFNGAF
GQDRVVGFTSNDKLVFLGVQGVLPNDDFRAHASMVGQDTVLKFGGDSVTL
VGVALNSLSADGIVIA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2zj6 Chain A Residue 624 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2zj6 Importance of the Ca2+-binding sites in the N-catalytic domain of a family I.3 lipase for activity and stability
Resolution2.25 Å
Binding residue
(original residue number in PDB)		G521 G523 D525 S538 G540 D543
Binding residue
(residue number reindexed from 1)		G520 G522 D524 S537 G539 D542
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.3: triacylglycerol lipase.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:2zj6, PDBe:2zj6, PDBj:2zj6
PDBsum2zj6
PubMed18987131
UniProtQ9RBY1

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